pp59fynand pp62c-yesare enriched in SH-SY5Y neuroblastoma growth cones but do not associate to the 38 kDa protein which complexes with pp60c srcand pp60c-srcN

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A complex consisting of pp60"/pp60 and a 38 kDa protein is highly enriched in growth cones from differentiated SH-SY5Y neuroblastoma cells

Nerve growth cones of primary neurons are highly enriched in the proto-oncogene product pp^'TM. In order to investigate this molecule further in growing neuronal cells, growth cone and cell body fractions were prepared from human SH-SY5Y neuroblastoma cells differentiated neuronally in vitro under the influence of phorbol ester. The fractions were characterized ultrastructurally and by biochemi...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 1993

ISSN: 0014-5793

DOI: 10.1016/0014-5793(93)80475-a